Program Medium
Internet-based program
Method of Physician Participation Utilized in Learning Process
There are no fees for participating and receiving CME credit for this activity. During the period April 4, 2019 through April 4, 2021, participants must 1) read the learning objectives and faculty disclosures; 2) study the educational activity, and are expected to view all 162 segments, totaling 6.0 hours, to successfully complete the activity and earn CME credit; 3) register and complete the evaluation form and post-test; 4) score 100% on the post-test; and 5) print out CME certificate.
Estimated Time to Complete Educational Activity
6.0 hours. Physicians must study the enduring activity, and are expected to view every segment to successfully complete the activity and earn CME credit.
Course Overview
In this web-based program, physicians will learn how recent developments in basic and clinical research have helped to advance the understanding and application of PCSK9 inhibitor-based therapies in the management of hypercholesterolemia.
Release Date
April 4, 2019
Expiration Date
April 4, 2021
Intended Audience
This complimentary CME educational activity is designed for all healthcare providers (HCPs) involved in developing, delivering, consulting, and monitoring care for patients who have high levels of LDL-C, including medical and preventive cardiologists, interventional cardiologists, lipid specialists, atherosclerosis specialists, diabetes specialists, endocrinologists, and related clinicians.
Registration
Participation in this iQ&A interactive Medical Intelligence Zone is complimentary, and clinicians are invited to view this CME-certified program and/or share this invitation with other colleagues, departmental staff members, and healthcare professionals.
Grantor Support
This activity is supported by an independent medical education grant from Sanofi Genzyme and Regeneron Pharmaceuticals.
Accreditation Statement
This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Postgraduate Institute for Medicine and CMEducation Resources, LLC. The Postgraduate Institute for Medicine is accredited by the ACCME to provide continuing medical education for physicians.
Credit Designation Statement
The Postgraduate Institute for Medicine designates this enduring material for a maximum of 6.0 AMA PRA Category 1 Credits(s). Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Policy on Faculty & Provider Disclosure
It is the policy of the Postgraduate Institute for Medicine to ensure fair balance, independence, objectivity and scientific rigor in all activities. All faculty participating in CME activities sponsored by the Postgraduate Institute for Medicine are required to present evidence-based data, identify and reference off-label product use and disclose all relevant financial relationships with those supporting the activity or others whose products or services are discussed. Faculty disclosure will be provided in the activity materials.
Program Faculty and Disclosure
Dan Atar, MD
Head of Research
Oslo University Hospital Ulleval
Professors of Cardiology
University of Oslo
Oslo, Norway
Visiting Associate Professorship
Johns Hopkins University
Baltimore, Maryland
Consultant: Amgen, Sanofi
Christie M. Ballantyne, MD
Director, Center for Cardiovascular Disease Prevention
Methodist DeBakey Heart Center
Chief of the Section of Cardiovascular Research
Baylor College of Medicine
Director of Atherosclerosis Laboratory
Professor of Medicine
Baylor College of Medicine
Houston, TX
Grant/Research Support (all paid to institution, not individual):Abbott Diagnostic, Amarin, Amgen, Esperion, lonis, Novartis, Pfizer, Regeneron, Roche Diagnostic, Sanofi Synthelabo, NIH, AHA, ADA Consultant/Independent Contractor:Abbott Diagnostics, Amarin, Amgen, AstraZeneca, Boehringer lngelheim, Eli Lilly, Esperion, lonis, Matinas BioPharma Inc, Merck, Novartis, Pfizer, Regeneron, Roche Diagnostic, Sanofi-Synthelabo
Deepak L. Bhatt, MD, MPH
Executive Director of Interventional Cardiovascular Programs
Brigham and Women’s Hospital Heart and Vascular Center
Professor of Medicine
Harvard Medical School
Boston, Massachusetts
Contracted Research: Abbott, Amarin, Amgen, AstraZeneca, Bristol-Myers Squibb, Chiesi, Eisai, Ethicon, Forest Laboratories, Idorsia, Ironwood, Ischemix, Lilly, Medtronic, PhaseBio, Pfizer, Regeneron, Roche, Sanofi Aventis, The Medicines Company
Michael J. Blaha, MD, MPH
Director of Clinical Research Ciccarone Center for the Prevention of Heart Disease
Associate Professor of Medicine
Johns Hopkins School of Medicine
Baltimore, MD
Consultant: Amgen, Sanofi, Regeneron, Novo Nordisk, Novartis, Medicure Research Support: Amgen, Aetna
Alberico Catapano, PhD
Full Professor of Pharmacology
University of Milano
Director, Laboratory for the Study of Lipoproteins and Atherosclerosis
Director, Center for the Study of Atherosclerosis of the Italian Society of Atherosclerosis
Bassini Hospital
Director, Center of Epidemiology and Preventive Pharmacology
University of Milano (SEFAP)
Immediate Past President, European Atherosclerosis Society (EAS)
Honoraria, Speaker Fees, or Grant Support: Abbott, Aegerion, Amgen, AstraZeneca, Bayer, Eli Lilly, Genzyme, Ionis, Kowa, Mediolanum, Meda, Menarini, Merck, Pfizer, Recordati, Regeneron, Sanofi, and SigmaTau
Michael H. Davidson, MD, FACC, FACP, FNLA
Clinical Professor
Director of Preventive Cardiology
The University of Chicago Hospitals and Clinic
Pritzker School of Medicine
Chicago, Illinois
Consultant: Amgen, Regeneron, Sanofi
Stefano Del Prato, MD PhD
Professor of Endocrinology and Metabolism
School of Medicine, University of Pisa
Chief of the Section of Diabetes
University of Pisa, Italy
Clinical Associate Professor of Medicine
University of Texas, San Antonio Health Science Center
San Antonio, TX
Advisory Panel; Self; AstraZeneca, Boehringer Ingelheim Pharmaceuticals, Inc., Eli Lilly and Company, GlaxoSmithKline plc., Intarcia Therapeutics, Inc., Merck & Co., Inc., Novartis Pharmaceuticals Corporation, Novo Nordisk A/S, Servier, Sanofi, Takeda Pharmaceuticals U.S.A., Inc.. Research Support; Self; Merck & Co., Inc., Novartis Pharmaceuticals Corporation, Boehringer Ingelheim Pharmaceuticals, Inc., AstraZeneca. Speaker's Bureau; Self; Boehringer Ingelheim Pharmaceuticals, Inc., Novartis Pharmaceuticals Corporation, Takeda Pharmaceuticals U.S.A., Inc.. Advisory Panel; Self; Janssen Biotech, Inc., Abbott.
Sergio Fazio, MD
Director, Center for Preventive Cardiology
Professor of Medicine
Division of Cardiovascular Medicine
School of Medicine
Oregon Health Sciences University (OHSU)
Portland, OR
Consultant/Advisor: Aegerion Pharmaceuticals, Amarin Corporation, Ackea Therapeutics, Inc., Amgen Inc., Kowa Pharmaceuticals America, Inc.
Vivian A. Fonseca, MD, FRCP
Professor of Medicine and Pharmacology
Tulis-Tulane Alumni Chair in Diabetes
Chief, Section of Endocrinology
Tulane University Health Sciences Center
New Orleans, LA
President, Science and Medicine (2012)
American Diabetes Association (ADA)
Research Support (To Tulane): Grants from Asahi, Bayer Consulting and Speaking: Takeda, Novo Nordisk, Sanofi-aventis, Eli Lilly, Astra-Zeneca, Janssen
Keith A.A. Fox, MBChB, FRCP, FMedSci
Professor, University of Edinburgh
Department of Cardiovascular Medicine
Professor, University and Royal Infirmary
Edinburgh, United Kingdom
Consultant: AstraZeneca Pharmaceuticals LP; Bayer AG; Janssen Pharmaceuticals; Regeneron Pharmaceuticals, Inc.; Sanofi Speaker: AstraZeneca Pharmaceuticals LP; Bayer AG; Janssen Pharmaceuticals Received grants for clinical research from: AstraZeneca Pharmaceuticals LP; Bayer AG; Janssen Pharmaceuticals
Anne C. Goldberg, MD, FNLA, FACP, FAHA
Professor of Medicine
Division of Endocrinology, Metabolism & Lipid Research
Washington University
St. Louis, MO
Consultant: Experion, Optum Rx, Sanofi, Regeneron, Novartis, Akesa Research Support: Merck, Sanofi, Regeneron, Amgen, Pfizer, Amarin, Alecea/IONIS
Samuel Z. Goldhaber, MD
Professor of Medicine
Harvard Medical School
Interim Chief, Division of Cardiovascular Medicine
Director, Thrombosis Research Group
Cardiovascular Division
Head, Vascular Medicine
Brigham and Women's Hospital
President, North American Thrombosis Forum (NATF)
Boston, Massachusetts
Consultant and Research Support: Boehringer Ingelheim, Bristol-Myers Squibb, BTG EKOS, Daiichi, Janssen Thrombosis Research Institute Research Support Consultant: Agile, Bayer, Portola, Soleno
Shaun Goodman, MD, MSc, FRCPC, FACC, FESC, FAHA
Associate Head, Division of Cardiology
St. Michael’s Hospital
Professor, Department of Medicine
University of Toronto
Toronto, Ontario
Consulting: Amgen, Sanofi, Regeneron, AstraZeneca, Bristol Myers Squibb, Merck, Pfizer Speaker: Amgen, Sanofi, Regeneron Research Support: Amgen, Sanofi, Regeneron
J. Wouter Jukema, MD, PhD, FESC, FACC MC
Professor of Cardiology
Netherlands Heart Foundation
Chairman, Leiden Vascular Medicine
Leiden University Medical Center (LUMC)
Leiden, Netherlands
Research Support or CME Speaker Fees: Amgen, Astra-Zeneca, Biotronik, Daiichi Sankyo, Lilly, Merck-Schering-Plough, Pfizer, Sanofi Aventis, The Medicine Company, the Netherlands Heart Foundation, CardioVascular Research the Netherlands (CVON), the Interuniversity Cardiology Institute of the Netherlands, and the European Community Framework KP7 Program
Ulf Landmesser MD, FESC
Professor of Cardiology
Medical Director, Department of Cardiology
Charite University Hospital
Berlin, Germany
Consultant: Sanofi, Amgen, Medicines Company
Lawrence A. Leiter, MD, FRCP(C), FACP
Head, Division of Endocrinology and Metabolism
Director, Lipid Clinic
Associate Director, Clinical Nutrition and Risk Factor Modification Centre
St. Michael’s Hospital
Professor, Medicine and Nutritional Sciences
University of Toronto
Toronto, Ontario, Canada
Consulting: Astra Zeneca, BI, Eli Lilly, Janssen, Merck, Novo Nordisk, Sanofi, Servier Speakers Bureau: Astra Zeneca, BI, Eli Lilly, Janssen, Merck, Novo Nordisk, Sanofi Contracted Research: Astra Zeneca, BI, Eli Lilly, GSK, Janssen, Merck, Novo Nordisk, Pfizer, Sanofi, Servier
Stephen J. Nicholls, MD
SAHMRI Deputy Director and Heart Foundation Heart Health Theme Leader
Professor of Cardiology
University of Adelaide
Consultant Cardiologist
Royal Adelaide Hospital
Adelaide, Australia
Research Support: AstraZeneca, Amgen, Anthera, Eli Lilly, Esperion, Novartis, Cerenis, The Medicines Company, Resverlogix, InfraReDx, Roche, Sanofi-Regeneron and LipoScience Consultant: AstraZeneca, Eli Lilly, Anthera, Omthera, Merck, Takeda, Resverlogix, Sanofi-Regeneron, CSL Behring, Esperion and Boehringer Ingelheim
Paul Ridker, MD
Eugene Braunwald Professor
Harvard Medical School
Division of Cardiovascular Medicine
Director, Center for Cardiovascular Disease Prevention
Brigham and Women’s Hospital
Boston, MA
Consultant: Corvidia; Eisai Inc.; Inflazome Ltd.; Janssen Pharmaceuticals; Novartis Pharmaceuticals Corporation; Quintiles Transnational Corp.; Sanofi Research Suport: Amgen Inc.; AstraZeneca Pharmaceuticals LP; Kowa Company Ltd.; Novartis Pharmaceuticals Corporation; Pfizer Inc. Other: Co-inventor on patents licensed to AstraZeneca Pharmaceuticals LP and Siemens AG
Matthew T. Roe, MD
Professor of Medicine
Duke Clinical Research Institute
Duke University School of Medicine
Durham, NC
Nothing to disclose
Robert S. Rosenson, MD
Professor of Medicine (Cardiology)
Mount Sinai Icahn School of Medicine
Director, Cardiometabolics Unit
Mount Sinai Heart Institute
New York, NY
Consulting: Amgen Speaker: Amgen Research Support: Amgen, Regeneron, Medicines Company
Christian Ruff, MD
Principal Investigator, ENGAGE-AF Trial
TIMI Group
Director, General Cardiology
Brigham and Women’s Hospital
Assistant Professor of Medicine
Harvard Medical School
Boston, MA
Consultant: Bayer; Boehringer Ingelheim; Daiichi Sankyo; Portola Pharmaceuticals, Inc. Research Support: Daiichi Sankyo
Phillipe Gabriel Steg, MD
Professor of Cardiology
Université Paris – Diderot, Sorbonne-Paris Cité
Professor, National Heart and Lung Institute
Imperial College, London, UK
Director, Coronary Care Unit
Hôpital Bichat
Paris, France
Advisor or consultant: Amarin Corporation plc; Amgen Inc.; AstraZeneca Pharmaceuticals LP; Bayer HealthCare Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals, Inc.; Bristol-Myers Squibb Company; Janssen Pharmaceuticals; Lilly; Merck & Co., Inc.; Novartis Pharmaceuticals Corporation; Novo Nordisk; Pfizer Inc.; Regeneron Pharmaceuticals, Inc.; Sanofi; SERVIER Speaker: Amarin Corporation plc; Amgen Inc.; AstraZeneca Pharmaceuticals LP; Bayer HealthCare Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals, Inc.; Bristol-Myers Squibb Company; Janssen Pharmaceuticals; Lilly; Merck & Co., Inc.; Novartis Pharmaceuticals Corporation; Novo Nordisk; Pfizer Inc.; Regeneron Pharmaceuticals, Inc.; Sanofi; SERVIER Research Support: Bayer HealthCare Pharmaceuticals; Merck & Co., Inc.; Sanofi; SERVIER
Eric Stroes, MD, PhD
Professor
Department of Vascular Medicine
Academic Medical Center
Amsterdam, The Netherlands
Nothing to disclose
Freek W A Verheugt, MD, PhD
Professor of Cardiology
Chairman of the Department of Cardiology
Heartcenter of the University Medical Center
Nijmegen, The Netherlands
Advisor or Consultant Bayer AG; Bristol-Myers Squibb Company/Pfizer Inc. Speaker: Boehringer Ingelheim; Daiichi Sankyo
Vincent Woo, MD, FRCPC
Endocrinology and Metabolism
University of Manitoba
Principal Investigator
Diabetes Research Group
John Buhler Research Centre
Winnipeg, Manitoba, Canada
Nothing to disclose
R. Scott Wright, MD
Professor of Medicine
Department of Cardiovascular Medicine
Cardiovascular Division
Mayo Clinic
Consultant: Sanofi, Regeneron, Boehringer Ingelheim, The Medicines Company, AstraZeneca
Andreas Zeiher, MD
Chairman of Medicine
Department of Cardiology, Angiology, and Nephrology
J. W. Goethe University
Frankfurt, Germany
Consultant: Sanofi, Amgen, Boehringer Ingelheim
Upon completion of this activity, participants will be able to:
Hardware and Software Requirements:
To participate in this program, viewers must have a PC or Macintosh computer that has active, ongoing internet access for the duration of the program, as well as a compatible Flash-viewer. An email address is required for registration, and a printer is required to print out the CME certificate.
Privacy Policy
When you participate in a CME activity offered by CMEducation Resources, we ask you for your name, degree, affiliation, street address, telephone number, fax number, and/or e-mail address (the "Information"). We use that Information in the following ways:
Disclaimer
Copyright © 2019 by CMEducation Resources, LLC All rights reserved.
Reproduction, distribution, or translation without express written permission is strictly prohibited.
Content on this webcast reflects the opinions, output, and analyses of experts, investigators, educators, and clinicians whose activities for, while independent, are commercially supported by the sponsor noted at the start of each activity.
Content on this webcast is not meant to be, nor substitute for national guidelines or recommendations generated by professional, academic societies, colleges, or associations.
Content on this webcast is intended for educational value only. Its contents, analyses, and any recommendation made herein are intended to make scientific information and opinion available to health professionals, to stimulate thought, and further investigation. This webcast is not designed nor is any aspect of the contents here intended to provide advice regarding medical diagnosis or treatment for any individual case. Any decisions regarding diagnosis and/or management of any individual patient or group of patients should be made on individual basis after having consulted appropriate sources, whether they be appropriate consultants and/or guidelines and recommendations issued by national organizations, professional societies, governmental health organizations, or similar bodies. This webcast is not intended for use by the layman.
Opinions expressed herein are not necessarily those of Pharmatecture, LLC, CMEducation Resources, LLC, program supporters or accreditors, but reflect the opinions and analyses of the experts who have authored the material. Mention of products or services does not constitute endorsement. Clinical, legal, financial, and other comments are offered for general guidance only; and professional counsel should be sought for all specific situations.
